Pellets as a multiparticulate system gain much attraction in various drug delivery system approaches. In case of sustained release or controlled release formulations, pellets give promising results weather in capsule form or as pelltab (pellets compressed into tablet). For this study purpose, pellets were prepared by extrusion-spheronization technique and estimated by UV spectrophotometer (in bulk and in formulations). Different batches were formulated by applying 22 full factorial design using guar gum as release controlling polymer. Batch G3 and G4 possessed good ability to release drug completely from the formulation within 12 hrs. Other parameters were found with good acceptability. From the result of the present study, its clear that guar gum can be used as drug release controlling polymer to formulate extended release or sustained release or controlled release formulations as it found to be significant factor to control the drug release from pellets.
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